Allan Bream, Bioprocess Specialist at CRB, was recently featured in Pharma’s Almanac, with an article entitled, “Isolator Design in Cell Therapy Facilities.”
Cell and gene therapy manufacturing must be performed under aseptic conditions and with good aseptic handling practices to ensure patient safety. The use of isolators can help address this critical need, but designing isolators for advanced therapy medicinal product (ATMP) processes can be challenging.
Noel Maestre, PE and Emily Thompson, PE will be conducting a webinar via Cell and Gene Therapy Insights on how to deliver multi-product or multimodal Advanced Therapy Medicinal Product (ATMP) facilities to adapt to an evolving product pipeline.
Supporting our recent project growth in southern California, CRB is pleased to announce we’ve opened a new office in Tustin, Calif. The location will allow us to attract the best talent in the southern California region, pursue new business in Orange County and assist new and ongoing projects affiliated with its office in El Segundo, Calif.
CRB’s David B. Korzuch Jr., PE; and Christopher J. Barbieri, PE detailed several energy-saving strategies that can be implemented into the HVAC system design of a pharmaceutical-grade clean room suite in Consulting Specifying Engineer (CSE).
CRB is proud to sponsor the 2020 ISPE Facilities of the Future Conference which will explore advancements in pharmaceutical technology and what pharmaceutical manufacturing facilities will look like in the future. Featuring technical and inspirational presentations from industry leaders already planning and building “facilities of the future” this conference will look at new manufacturing challenges, technologies, and regulatory factors impacting the ability of today’s companies to stay competitive and cost-effective.
Philip Lyman, PhD and Peter Walters will be speaking at Phacilitate Leaders World & World Stem Cell Summit 2020! Taking place January 21 – 24, 2020 in Miami, this event will bring together the entire ecosystem of the advanced therapies industry from all corners of the globe.
CRB is often called upon by our clients to uncover energy savings. In the November issue of Food Engineering, Jeremy Gualdoni explains an energy recovery strategy used for a confectionery client in “Solving the Energy Equation.”
Peter Walters’ “The Pain-Free Guide: Transitioning from Clinical Production to Commercial Manufacturing” was featured in Contract Pharma. The article describes how cell and gene therapy facilities face a unique set of challenges as they scale towards commercial production and require equally unique solutions.
Autodesk University, a learning community that connects many of today’s design and engineering experts from industries across architecture and construction, manufacturing, media and entertainment, will be held at the Sands Convention Center in Las Vegas, Nevada, November 18-21, 2019.
ISPE’s Company of the Year award honors a company that continually supports the society’s commitment to providing knowledge and best practices that help meet the technical challenges of the pharmaceutical manufacturing industry.
Stop by the CRB booth at ISPE’s Annual Meeting to meet our team and learn how we’re leveraging the latest technologies to design and build some of the most powerful facilities in the world—those that change people’s lives.
The International Institute for Sustainable Laboratories (I²SL) Annual Conference is the leading international conference focused on strategies to meet the challenges of energy efficiency and environmental sustainability in laboratories and related facilities. The conference is a technical forum where information is exchanged covering the life cycle of the laboratory from design to use.
Chelsea Stramel, Architectural Designer and Jake Adams, Process Engineer were featured in Contract Pharma’s “Designing a Successful Oligonucleotide Facility – Five questions you probably aren’t asking, but should.”
David Keith, Director of Strategic Facility Planning, and Debora Hankinson, Senior Strategic Facility Planner will teach a pre-conference course titled “Fundamentals of Space Planning and Space Management” at Tradeline Space Strategies 2019 in San Diego, California.
CRB is excited to announce that Can Aktar has been appointed the leader of the Basel office and Christian Goesker has joined as engineering, procurement and construction management (EPCM) director in Stuttgart.
What if you could see your manufacturing potential and determine your cell and gene therapy strategy before making a large capital investment? Whether it’s a unit operation, single process train or entire manufacturing plant, new technologies allow companies to study and validate potential processes earlier than ever before.
Niranjan Kulkarni, Grace Linton and Allan Bream were interviewed in Cell and Gene Therapy Insights on “How commercial biopharma experience is shaping cell and gene therapy facility design.” The interview will give you some intel to how facility design differs from other sectors and what unique parameters need to be accounted for before embarking on a new facility.
If you missed speakers Peter Walters and Emily Thompson, Process Engineers from CRB, on August 22nd, 2019 as they discussed the importance of automating advanced therapy manufacturing, QC testing and warehousing, especially considering the immense variety of materials required for the many individual products and processes, you can hear the recording now!
Delano, Minnesota city officials joined executives from Tuffy’s Pet Foods, CRB, Pinky Swear Foundation and Founding Fathers Pet Treats to celebrate the groundbreaking of Tuffy’s new pet treat facility on Wednesday, August 7th in Delano.
CRB’s Ryan McDonough, PE, and Marc Pelletier, Ph.D. presented a webinar on June 25, 2019, on modeling multiple variations of a typical gene-modified cell therapy facility enables both a thorough examination of company and industry-wide challenges, and exploration of alternative/future models for the cell & gene therapy manufacturing sector.
Join speakers Peter Walters and Emily Thompson, Process Engineers from CRB, on August 22nd, 2019 at 11:00 am EDT as they discuss the importance of automating advanced therapy manufacturing, QC testing and warehousing, especially considering the immense variety of materials required for the many individual products and processes.
The European Directorate for the Quality of Medicines announced that the highly purified water (HPW) monograph would be suppressed in 2019, and pharmaceutical companies were left to wonder about the implications this has for their operations. How will HPW become water for injection (WFI)?
The 2019 ISPE Biopharmaceutical Manufacturing Conference is being held June 18-20 in Boston, MA and focuses on innovation in production methods and technologies that enable a competitive and sustainable biopharmaceutical product supply for the future. From mAbs to viral vectors, oligos to ADCs, this conference will bring together experts that are developing, implementing, and operating advanced supply chains supplying high quality medicines to global markets.
On June 4, 2019 CRB project partner Independent Stave Company (ISCO) broke ground on construction of Commonwealth Cooperage, a new state-of-the art cooperage facility in Morehead, KY. Representatives from ISCO, CRB and local officials gathered for the ceremonial groundbreaking which signified the beginning of construction on the approximately 150,000 square feet, $67 million project.
Peter Walters, Advanced Therapy Medicinal Product Subject Matter Expert and Kim Nelson, Senior Director, Strategic Consulting, at CRB were interviewed by Cell and Gene Therapy Insights on “Designing Facilities and Processes with Commercialization in Mind.”
Matthew Khair, Maryland Office Leader/Senior Associate, and J. Lee Emel, Southeast Regional Leader/Senior Associate at CRB are featured in Pharma’s Almanac’s current issue, entitled “Reducing Waste with Lean Delivery in Facility Design and Construction.”
CRB’s Marc Pelletier, Ph.D. will be presenting a webinar on June 25, 2019, on modeling multiple variations of a typical gene-modified cell therapy facility enables both a thorough examination of company and industry-wide challenges, and exploration of alternative/future models for the cell & gene therapy manufacturing sector.
On May 2, the Kansas City Business Journal honored CRB as one of the publication’s Champions of Business. Each year, the Kansas City Business Journal honors 15 companies that are rooted in Kansas City, have been in business at least three years and earn a gross revenue of at least $3 million. The Champions of Business winners are acknowledged as helping the community thrive.
The American Biomanufacturing Summit is being held June 18-19 in San Francisco, California and is designed to provide biopharmaceutical executives with current trends, strategic insights and best practices in manufacturing, outsourcing, capacity management, quality assurance, quality control, regulatory compliance, operational excellence, supply chain and logistics.
Laboratories are some of the most technically challenging types of spaces to design. Once the technical aspects are accounted for, what separates the good labs from the great? The answer lies in productivity.
The ISPE Canada Annual Education and Product Symposium is being held May 6-7 in Toronto, Canada and aims to inspire progress through education, operational excellence, product knowledge and interaction.
Tom Rychlewski and Larry Klein are featured in Food Processing’s “2019 Capital spending outlook: Building bigger.” The annual capital spending survey forecasts a 16.6 percent boost as food + beverage producers pump up the size of their building projects.
ISPE’s Facility of the Year Awards (FOYA) is the premier global awards program, recognizing innovation and creativity in the pharmaceutical and biotechnology manufacturing industries. Projects selected for recognition set the standard by demonstrating excellence in facility design, construction and operations.
Jeff Matis, PE and Tammi McAllister are featured in Food Engineering’s “A sustainable bottom line: Environmentally friendly upgrades must save money.” The costs and rewards of sustainable design in modern food and beverage manufacturing facilities are explained in the article.
Niranjan Kulkarni, Ph.D. and Steve Pflantz, PE are featured in Food Engineering’s March 2019 cover story, “The digitalization journey: Use segmented digitization to be competitive in a lasting, affordable way.” The article details planning and executing a successful implementation of digital techniques to improve processes, increase efficiency and obtain actionable information from them.
CRB’s Kansas City office is hosting a thoughtful panel discussion on the intersections or crossovers between public and private science. We will hear from experienced professionals as they answer questions and share insights into the latest trends and predictions for the future of research as well as innovation in technology, business and regional development.
The demand for CGMP clinical batch trial suites are on the rise at academic institutions, and rigorous grant application and facility design and construction requirements must be navigated with precision.
CRB’s Ryan McDonough is featured in this month’s The Medicine Maker. His article, “NextGen Now: Delivering Tomorrow’s Facilities Today” discusses how cell and gene therapy products will successfully reach patients and deliver transformative cures, however the industry will need more facilities capable of manufacturing them.
Dave DiProspero will be presenting at the 2019 ISPE Europe Annual Conference on Wednesday, April 3 alongside Steve Marr, head of capital engineering/global manufacturing and supply for Takeda/Shire and Tony Crincoli, vice president of engineering for Glenmark Pharmaceuticals.
Celebrating 40 years, INTERPHEX has been, and continues to be, the premier pharmaceutical, biotechnology, and device development and manufacturing event where you can “Experience Science through Commercialization”. Sponsored by the Parenteral Drug Association (PDA), the event is based in New York and brings over 10,500 global industry professionals and 620+ industry leading suppliers together to “Learn it, Experience it, Procure it” through a unique combination of no cost technical conference, exhibits, demonstrations, roundtables, partnering opportunities and networking to leverage quality, efficiency and cost effectiveness in today’s ever-changing global market.
Pilot plants represent a milestone in a drug’s commercial development, where drug sponsors first explore engineering, commercialization, clinical, regulatory, and process issues outside the relative safety of laboratory scale. And, as the test ground for a product’s ultimate manufacturability, pilot scale is where drug sponsors often return to de-bottleneck or to solve unanticipated production issues.
In today’s age of technology, manufacturers must guard themselves against cyberattacks. Automation and integration create more efficient facilities but can leave companies exposed if not properly secured.
The 2019 ISPE Aseptic Conference being held March 18-19 in North Bethesda, MD, focuses on the future of aseptic processing, including containment, multi-product facilities, and the increasing use of robotics. The attendees at the Aseptic Conference will be looking to not only learn about best practices in the industry, they also want to find out what are the latest and greatest in aseptic processing technologies.