Duckworth talks downstream automation in BioPharm International
Aug 12, 2022
Yvonne Duckworth, CRB’s Director of Digital Technology, was recently featured in “Developing Automation Downstream” in BioPharm International.
As upstream processes for monoclonal antibodies (mAbs) intensify, biopharmaceutical manufacturers are searching for new ways to meet production downstream.
Biopharma manufacturers are finding new and innovative ways to generate larger volumes of mAb product within their processes and facilities. These methods range from intensifying purification by using several chromatography columns in parallel and automating dead-end filtration skids for continuous depth-filtration, to intensifying buffer prep with in-line dilution of concentrated buffer solutions. “Intensified processes rely on process analytical technology (PAT) to collect real-time data used for automated process control.”