Revolutionize oligonucleotide manufacturing for life-changing therapies.

Capitalize on oligo market momentum.

As more drugs achieve FDA approval and demand increases, your industry is positioned for rapid expansion. But without an established industry standard for your production facility, navigating the transition from clinical to commercial scale is daunting.

How can CRB help you?

Leading oligo researchers and manufacturers come to us as a pioneering force guiding this industry in its commercial infancy. With decades of commercial manufacturing experience to draw from, our engineers devise creative, risk-based solutions for large-scale production based on similar technologies and extensive experience working with oligos in clinical development.

We have been actively involved in the development of oligos from the start. We are as invested as you are in designing efficient, effective and compliant oligo facilities to make these life-saving therapies more widely available.

Let’s envision the future of oligo manufacturing together.

Tell us about your project; we’ll make it a reality.

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What we do:

Don’t decide between product quality and production efficiency.

You can have a more efficient, more sustainable, lower cost facility that produces the best quality pharmaceutical products for your patients. Get a customized, best-in-class solution from experts who possess extensive knowledge and experience in all aspects of pharma manufacturing.

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Make APIs faster, cheaper and with less waste.

It’s not enough to build a functional bulk pharmaceuticals manufacturing facility; you must meet increasingly more rigorous safety and quality standards, while producing APIs quickly and efficiently. Get a solution for your new or existing facility to achieve your business aims, and most importantly, find opportunities to improve upon your process.

Reduce your animal health project timeline and lower capital costs with lead design and construction execution.

Animal health affects billions of people worldwide, so it’s vitally important that your products are effective and safe. How do you do that when the cost margin is low?
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Mitigate the risks of your most complex aseptic processes.

Every component matters in aseptic processing—especially the people designing and building your facility. The safety and efficacy of your product relies on the coordination and interaction of personnel, equipment, facility and the product. Cleanliness and contamination control must be engineered and built in.

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Improve your plasma fractionation processing with innovative solutions.

Clean, streamline and simplify your bulk processing facility with the right design and regulatory expertise. From process utilities to equipment, get a solution that includes the mixing, liquid transferring and chilling, filtering and clean-in-place considerations needed to maximize your cleanability and efficiency, while minimizing operator intervention. No matter the extent of your project, our team builds value into your human plasma-derived therapeutics facility by finding the best opportunities to improve your outcomes while ensuring compliance to applicable codes.

Patients are relying on your OSD drug product.

Because a well-designed process is central to your success, the right process solution is also unique to you. Whether you’re ready to enter the continuous manufacturing arena or you’re looking to achieve a wider range of capabilities with a more robust CM system, implement the process that’s best for your business.

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