Spray drying is a rapid, robust, reproducible, and scalable process.Read More
Senior Fellow - Pharmaceutical Process
Dave DiProspero has 25 years of pharmaceutical engineering experience with a specialty in oral solid dose (OSD) form manufacturing operations/facilities/equipment/technology. His primary expertise is in internationally regulated, cGMP operations with a strong engineering, process, containment, equipment, material handling and facility systems integration background.
Dave is experienced in site master planning, conceptual/preliminary/detailed facility design, engineering, procurement, qualification, project management and facility assessments. He has a solid understanding of FDA 21-CFR Parts 210 & 211, EU Volume 4 and other international pharma regulations.
Dave has also been involved in equipment/facility/systems integration and project coordination/management. He has worked as an owner’s representative and as a direct employee for many well-known equipment/technology suppliers and engineering firms.
As a director of pharmaceutical process technology (and an OSD subject matter expert), Dave provides project oversight and is involved in front-end/back-end project consultation and planning, strategizing, implementation/execution and is an experienced team communicator. Dave has specific expertise in projects that include dispensing/formulating, blending/mixing, granulation/particle coating, drying, compression/encapsulation, tablet coating/printing, packaging and other typical and non-typical OSD processes.
He is a long-term member of the International Society for Pharmaceutical Engineering and has chaired numerous committees–many related to education. He is currently the chair of the Facility of the Year Committee and steering committee advisor of the OSD Community of Practice. He is the steering committee manager for the OSD Baseline Guide Volume 3 revision effort.
Dave frequently speaks, writes and teaches on various industry topics and was the recipient of the 2006 ISPE Max Seales Yonker Member of the Year award.
Insights By Dave
Oral solid dosage manufacturing
Oral solid dosage (OSD) products can take several different shapes, and with those different forms comes different production techniques and facility designs. Here’s what is involved with manufacturing an orally-ingested drug product.Read More
The basics and the process of drug approval
The COVID-19 pandemic has put the spotlight on the FDA drug approval process. Why will it take so long for a vaccine to get approved?Read More
A COVID-19 roadmap for oral solid dosage manufacturers
OSD products may find themselves thrust into the spotlight as their effectiveness against the symptoms of COVID-19 becomes known.Read More
Continuous OSD manufacturing—a technology update
Continuous oral solid dosage manufacturing is a transformational processing platform that is here today and is here to stay. Although the industry is working on harmonization and some level of standardization of the platforms, continuous manufacturing is not a one-size-fits all offering.Read More